Southeastern Indiana Vacation Packages 2026 from $624

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Your Southeastern Indiana Vacation

Head off on your next big adventure with a Southeastern Indiana vacation package, and leave knowing all the details are organized. And with the ability to customize your getaway, you know it'll be one to remember. Your trip to Southeastern Indiana wouldn't be complete without getting to some of its most well-known cities, starting with Louisville. A couple of the top attractions here include KFC Yum Center and Kentucky Kingdom. Radcliff should also be on the itineraries of all Southeastern Indiana travelers. Visitors to this exciting city love Freeman Lake Park and General George Patton Museum. Whether you're planning to travel for a few days or a few weeks, Expedia are here to help you tailor-make your next dream Southeastern Indiana vacation.

The Latest Southeastern Indiana vacation packages

Price found within the past 48 hours. Click for updated prices.

Holiday Inn Louisville Airport South by IHG

$624

per person

Dec 4 - Dec 11

just found

Roundtrip flight included

Fort Lauderdale (FLL) to Louisville (SDF)

8.8/10 Excellent! (1,003 reviews)

Amazing over all

Reviewed on Sep 24, 2026

Cottonwood Airport & Expo Hotel Louisville

Shively

Save 100% on your flight

$716

per person

Dec 4 - Dec 11

just found

Roundtrip flight included

Fort Lauderdale (FLL) to Louisville (SDF)

8.6/10 Excellent! (1,004 reviews)

While the hotel was quite nice and the staff was very friendly and helpful, I found the "pet friendly" part of the description misleading. Some hotels state they are "pet ok with fee's" and you expect a fee at every hotel that allows pets, however I was surprised at the amount. I think all hotels that accept pets should be more specific in their information. The fee here was $40, a bit higher than expected. If pet fees were included with the descriptions they could be compared in the same way you include the room rates, helping to make a decision. Otherwise this was a very nice hotel at a reasonable cost.

Reviewed on Sep 23, 2026

The Grady

Downtown Louisville

Save 100% on your flight

$859

per person

Dec 4 - Dec 11

found 1 hour ago

Roundtrip flight included

Fort Lauderdale (FLL) to Louisville (SDF)

9.4/10 Exceptional! (1,005 reviews)

The bed was incredibly uncomfortable and lumpy. The pillows screwed up my neck. However, Kevin and Farrah at the front desk were incredibly helpful. We ate at the hotel restaurant and the food was good. Overall, the people working there were great! The beds and pillows were not to my liking but that was my only issue.

Reviewed on Sep 23, 2026

The Brown Hotel

Downtown Louisville

Save 100% on your flight

$700

per person

Dec 4 - Dec 11

just found

Roundtrip flight included

Fort Lauderdale (FLL) to Louisville (SDF)

9.4/10 Exceptional! (1,289 reviews)

Great stay

Reviewed on Sep 24, 2026

TownePlace Suites by Marriott Louisville Airport

$737

per person

Dec 4 - Dec 11

found 1 hour ago

Roundtrip flight included

Fort Lauderdale (FLL) to Louisville (SDF)

9.2/10 Wonderful! (223 reviews)

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Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

Madison Historic District

If you're spending some time in Madison Historic District, Historic District and Lanier Mansion are top sights worth seeing.

A bridge with a metal truss structure and a highway with vehicles.

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

An aerial view of a park with manicured lawns, a central fountain, and a large building with a red dome.

Downtown French Lick

While Downtown French Lick might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like French Lick Springs Hotel and French Lick Casino.

A weathered tower with a metal sign reading "Better By Far" and a metal structure with the number "3" on top.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

Stay near popular Southeastern Indiana attractions

A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)

Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

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A wooden barrel room with barrels lined up on both sides and a wooden floor.

Whiskey Row

9.2/10 (11 reviews)

Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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A city street with a large building labeled "FOURTH STREET" and a neon sign for "JIM BEAM."

Fourth Street Live!

8.4/10 (2,560 reviews)

You can do some window-shopping at Fourth Street Live! during your stay in Louisville. Experience the area's entertainment choices and lively festivals.

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A waterfall cascading over a rocky cliff surrounded by dense green foliage.

Clifty Falls State Park

9.2/10 (183 reviews)

You can take time to visit Clifty Falls State Park during your travels to Madison. Stroll along the riverfront or discover the area's waterfalls.

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A nighttime cityscape with a lit bridge reflecting on the water.

Louisville Waterfront Park

8.8/10 (668 reviews)

After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its acclaimed art scene.

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Kentucky International Convention Center

8.4/10 (763 reviews)

Learn about the events happening at Kentucky International Convention Center during your trip to Louisville. Amble around the area's riverfront or attend a sporting event.

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Louisville Palace

8.2/10 (488 reviews)

You can get tickets for a performance at Louisville Palace on your trip to Louisville. Experience the area's acclaimed theater scene or attend a sporting event.

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Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North

505 Marriott Drive Clarksville IN

Fully refundable

$76 nightly

$85 total

Oct 1 - Oct 2

Total with taxes and fees

Derby Hotel & Suites

505 K Marriot Dr Clarksville IN

Fully refundableReserve now, pay when you stay

$60 nightly

$67 total

Sep 28 - Sep 29

Total with taxes and fees

7/10 Good! (209 reviews)

"Check in was easy and attendant was very friendly and nice to chat with, It’s a good budget hotel if all you need is a place to sleep and get ready for the day. Room was decent and the air conditioner worked very nice, it was nice to have a fridge to store some leftovers."

Reviewed on Sep 24, 2026

Hampton Inn New Albany Louisville West

411 W Spring Street New Albany IN

Fully refundableReserve now, pay when you stay

$98 nightly

$110 total

Oct 11 - Oct 12

Total with taxes and fees

See all 1,183 properties in Southeastern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.