Southeastern Indiana Vacation Packages 2026 from $280

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Your Southeastern Indiana Vacation

Head off on your next big adventure with a Southeastern Indiana vacation package, and leave knowing all the details are organized. And with the ability to customize your getaway, you know it'll be one to remember. Your trip to Southeastern Indiana wouldn't be complete without getting to some of its most well-known cities, starting with Louisville. A couple of the top attractions here include KFC Yum Center and Kentucky Kingdom. Radcliff should also be on the itineraries of all Southeastern Indiana travelers. Visitors to this exciting city love Freeman Lake Park and General George Patton Museum. Whether you're planning to travel for a few days or a few weeks, Expedia are here to help you tailor-make your next dream Southeastern Indiana vacation.

The Latest Southeastern Indiana vacation packages

Price found within the past 48 hours. Click for updated prices.

Radisson Hotel Cincinnati Riverfront

Central Business District

Save 100% on your flight

$280

per person

Oct 31 - Nov 3

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Cincinnati (CVG)

7.2/10 Good! (2,971 reviews)

The Purple Martin

Save 100% on your flight

$1,429

per person

Sep 16 - Sep 21

found 1 day ago

Roundtrip flight included

New York (LGA) to Louisville (SDF)

10/10 Exceptional! (2 reviews)

Amazing property… I would come back in a heartbeat!

Reviewed on Jun 19, 2025

Hotel Covington Cincinnati Riverfront

Central Business District

Save 100% on your flight

$370

per person

Oct 31 - Nov 3

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Cincinnati (CVG)

9.6/10 Exceptional! (1,014 reviews)

Holiday Inn Express West Cincinnati by IHG

Dent

Save 100% on your flight

$367

per person

Sep 8 - Sep 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Cincinnati (CVG)

8.4/10 Very Good! (1,004 reviews)

Great hotel , wonderful breakfast, comfortable

Reviewed on Aug 8, 2026

voco The Clair Cincinnati Downtown by IHG

Downtown Cincinnati

Save 100% on your flight

$843

per person

Sep 8 - Sep 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Cincinnati (CVG)

9.2/10 Wonderful! (1,316 reviews)

Great location, really enjoyed our room and the amazing shower!

Reviewed on Aug 8, 2026

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Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

A bridge with a metal truss structure and a highway with vehicles.

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

A weathered tower with a metal sign reading "Better By Far" and a metal structure with the number "3" on top.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

An aerial view of a park with manicured lawns, a central fountain, and a large building with a red dome.

Downtown French Lick

While Downtown French Lick might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like French Lick Springs Hotel and French Lick Casino.

Russell

If you're spending some time in Russell, Ohio River Valley and I. Willis Cole Residence are top sights worth seeing.

Stay near popular Southeastern Indiana attractions

A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)

Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

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A bridge with illuminated blue lights at night.

Louisville Waterfront Park

8.8/10 (668 reviews)

After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its great live music.

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A wooden barrel room with barrels lined up on both sides and a wooden floor.

Whiskey Row

9.2/10 (11 reviews)

Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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A city street with a large building labeled "FOURTH STREET" and a neon sign for "JIM BEAM."

Fourth Street Live!

8.4/10 (2,560 reviews)

You can do some window-shopping at Fourth Street Live! during your stay in Louisville. Experience the area's great live music and entertainment choices.

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A waterfall cascading over a rocky cliff surrounded by dense green foliage.

Clifty Falls State Park

9.2/10 (183 reviews)

You can take time to visit Clifty Falls State Park during your travels to Madison. Stroll along the riverfront or discover the area's waterfalls.

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Kentucky International Convention Center

8.4/10 (763 reviews)

Learn about the events happening at Kentucky International Convention Center during your trip to Louisville. Amble around the area's riverfront or attend a sporting event.

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Kentucky Bourbon Trail Visitor Center

Kentucky Bourbon Trail Visitor Center is just one of the places to see in Louisville, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North

505 Marriott Drive Clarksville IN

Fully refundableReserve now, pay when you stay

$60 nightly

$68 total

Aug 15 - Aug 16

Total with taxes and fees

7/10 Good! (3,309 reviews)

"It’s not a bad hotel but shows that it’s older. It would be nice if they had tables around the pool so people can sit, watch their kids and have a place to play a game while kids are swimming. Also some of the hallways were very hot, apparently no air conditioning in them."

Reviewed on Aug 7, 2026

Derby Hotel & Suites

505 K Marriot Dr Clarksville IN

Fully refundable

$57 nightly

$64 total

Aug 16 - Aug 17

Total with taxes and fees

Big Splash Adventure Indoor Water Park & Resort

8505 W State Road 56 French Lick IN

$148 nightly

$165 total

Aug 9 - Aug 10

Total with taxes and fees

7.8/10 Good! (204 reviews)

"Overall the family was enjoing verywell."

Reviewed on Aug 6, 2026

See all 1,144 properties in Southeastern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.